Nanopareil produces cutting-edge separation media composed of functionalized nanofibers. The product is manufactured from a randomly overlaidmat of electrospun nanofibers, which provide a unique separation medium capable of both size-based as well as adsorptive separation mechanisms. The highly advanced and proprietary formulation provides the opportunity to greatly enhance process efficiencies and economics in the antibody, vaccine, and blood product purification markets.
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Benefits of Nanopareil
Nanofiber Separations, LLC was born out of a project sponsored by the National Science Foundation (NSF) that began in 2006. In July of 2015 Nanofiber Separations, LLC officially changed its name to Nanopareil, LLC. During this five-year project, the company co-founders, Dr. Todd Menkhaus and Dr. Hao Fong, determined that a commercially available nanofiber product would be a significant improvement over existing adsorption and size-based separation media in several, high-value market segments. With this major unmet need for advanced purification devices confirmed in the marketplace, Nanopareil was organized as a limited liability company under the laws of the State of South Dakota in October, 2011. In February 2014, Nanopareil was awarded a National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase II Grant and in April of 2014, Nanofiber Separations received statewide recognition by winning the South Dakota Governor’s Giant Vision Business Plan Competition.
CHEMICAL COMMUNICATIONS. 46 (21), 3720-3722
Menkhaus, Todd J.; Varadaraju, Hemanthram; Zhang, Lifeng; Schneiderman, Steven; Bjustrom, Stephany; Liu, Li; Fong, Hao (2010). Electrospun nanofiber membranes surface functionalized with 3-dimensional nanolayers as an innovative adsorption medium with ultra-high capacity and throughput.
JOURNAL OF MEMBRANE SCIENCE, IN-PRESS (2014)
autam, A.K., Lai, C., Fong, H., Menkhaus, T.J. Electrospun Polyimide Nanofiber Membranes for High Flux and Low Fouling Microfiltration Applications.
JOURNAL OF CHROMATOGRAPHY A. 1218 (51), 9121-9127
Schneiderman, Steven; Varadaraju, Hemanthram; Zhang, Lifeng; Fong, Hao; Menkhaus, Todd J. (2011). Mathematical model using non-uniform flow distribution for dynamic protein breakthrough with membrane adsorption media.
JOURNAL OF CHROMATOGRAPHY A. 1218 (50), 8989-8995
Schneiderman, Steven; Zhang, Lifeng; Fong, Hao; Menkhaus, Todd J. (2011). Surface-functionalized electrospun carbon nanofiber mats as an innovative type of protein adsorption/purification medium with high capacity and high throughput.
BIOTECHNOLOGY PROGRESS. 27 (5), 1297-1305
Varadaraju, Hemanthram; Schneiderman, Steven; Zhang, Lifeng; Fong, Hao; Menkhaus, Todd J. (2011). Process and Economic Evaluation for Monoclonal Antibody Purification Using a Membrane-Only Process.
JOURNAL OF MEMBRANE SCIENCE. 369 (1-2), 499-505
Zhang, Lifeng; Luo, Jie; Menkhaus, Todd J.; Varadaraju, Hemanthram; Sun, Yuyu; Fong, Hao (2011). Antimicrobial nano-fibrous membranes developed from electrospun polyacrylonitrile nanofibers.
POLYMER. 51 (11), 2360-2367
Zhou, Zhengping; Liu, Kunming; Lai, Chuilin; Zhang, Lifeng; Li, Juanhua; Hou, Haoqing; Reneker, Darrell H.; Fong, Hao (2010). Graphitic carbon nanofibers developed from bundles of aligned electrospun polyacrylonitrile nanofibers containing phosphoric acid.
JOURNAL OF MEMBRANE SCIENCE, 319, 176-184 (2008)
Zhang, L.; Menkhaus, T.J.; and Fong, H. Fabrication and Bioseparation Studies of Adsorptive Nanofelts Made from Electrospun Cellulose Acetate Nanofibers.